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SPFH2 antibody, 內質網(wǎng)脂質轉運相關蛋白2抗體

 
編 號 PR-6642
產品名稱 SPFH2 antibody, 內質網(wǎng)脂質轉運相關蛋白2抗體
規(guī) 格 0.2ml
價 格 1980元
應 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細信息: 說明書下載

Background:  SPFH2 is a ubiquitously expressed 339 amino acid protein that belongs to the band 7/mec-2 family. Localized to lipid raft-like domains in the membrane of the endoplasmic reticulum (ER), SPFH2 plays a crucial role in the ER-associated degradation (ERAD) pathway that removes metabolically regulated and aberrant proteins from the ER. Specifically, SPFH2 associates with IP3R-I (Inositol 1,4,5-triphosphate receptor I), a substrate of the ERAD pathway, and facilitates its polyubiquitination and subsequent degradation. Three isoforms of SPFH2 are expressed due to alternative splicing events.

Description: Rabbit polyclonal to SPFH2

Immunogen: KLH conjugated synthetic peptide derived from SPFH2

Specificity:  ·Reacts with Human, Mouse, Pig, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 38 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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