Background:  The Jagged1 is a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. Jagged1 may be involved in cell-fate decisions during hematopoiesis and seems to be involved in early and late stages of mammalian cardiovascular development. Jagged1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).

Description: Rabbit polyclonal to Jagged1

Immunogen: KLH conjugated synthetic peptide derived from Jagged1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 150 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.