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CD130/gp130 antibody, CD130抗體

 
編 號(hào) PR-0174
產(chǎn)品名稱(chēng) CD130/gp130 antibody, CD130抗體
規(guī) 格 0.2ml
價(jià) 格 1980元
應(yīng) 用 IHC,WB,ELISA,ICC,IP,IF,FCM
品 牌 Hopebiot

詳細(xì)信息: 說(shuō)明書(shū)下載

Background:  CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Description: Rabbit polyclonal to CD130

Immunogen: KLH conjugated synthetic peptide derived from CD130

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 102 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-500;

·ELISA: 1/500;

·FCM: 1/20-100;

·Optimal working dilutions must be determined by the end user.

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