Background: NIT2 has an omega amidase activity. The role of omega amidase is to remove potentially toxic intermediates by converting alpha ketoglutaramate and alpha ketosuccinamate to biologically useful alpha ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
Description: Rabbit polyclonal to NIT2
Immunogen: KLH conjugated synthetic peptide derived from NIT2
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 31 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.