Background:  Brn3a (Brain-specific homeobox/POU domain protein 3A) is a transcription factor specifically expressed in cells of the developing mammalian nervous system. Brn3a is implicated in the regulation of specific gene expression within a subset of neuronal lineages and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Brn3a is expressed in enbryonic brain, peripheral sensory nervous system and retina. In the adult nervous system Brn3a is primarily found in the CNS: medial habenula, superficial gray of the superior colliculus, red nucleus, mesencephalic nucleus of the trigeminal ganglion, nucleus ambiguus, inferior olivary nucleus and peripheral sensory ganglia.

Description: Rabbit polyclonal to BRN3A

Immunogen: KLH conjugated synthetic peptide derived from BRN3A

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/200-1000. Predicted Mol wt: 43 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-500;

·ELISA: 1/1000;

·Optimal working dilutions must be determined by the end user.