Background: KLHL31, also known as kelch-like protein 31, BTB and kelch domain-containing protein 6, kelch-like protein KLHL or kelch repeat and BTB domain-containing protein 1, is a 634 amino acid protein similar to the Drosophila kelch protein. KLHL31 is expressed strongly in skeletal muscle and weakly in heart. KLHL31 contains one BACK (BTB/kelch associated) domain, which may indicate a role in substrate orientation in E3 ligase complexes. KLHL31 also contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function.

Description: Rabbit polyclonal to KLHL31

Immunogen: KLH conjugated synthetic peptide derived from KLHL31

Specificity:  ·Reacts with Human, Mouse, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/200-500. Predicted Mol wt: 70 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.