Background:  Teratocarcinoma-derived growth factor (TDGF)-1 gene encodes a protein known as Cripto-1. This gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that give rise to the mesoderm. Cripto-1 overexpression is characteristic of human gastric and colorectal carcinomas.

Description: Rabbit polyclonal to Cripto-1

Immunogen: KLH conjugated synthetic peptide derived from Cripto-1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 21 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;

·Immunocytochemistry: 1/100-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.