Background: The interleukins (ILs) are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. They are secreted by immune cells (mainly macrophages, B cells or T cells) that regulate a wide range of immune system functions. The specific functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. IL-29, also known as interferon-λ1 (IFN-λ1) is a class II cytokine that stimulates its response through a heterodimeric receptor composedof IL-10Rβ and IL-28RA. It is induced by viral infection and exhibits antiviral and antiproliferative activity. In addition, IL-29 may play a role in immunoregulation. It stimulates an identical response as IFN-α but utilizes a different receptor. In addition, IL-29 may be a useful therapeutic agent against chronic viral hepatitis.

Description: Rabbit polyclonal to IL29

Immunogen: KLH conjugated synthetic peptide derived from IL29

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 22 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.