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ALDH3A2 antibody, 脂肪醛脫氫酶抗體

 
編 號(hào) PR-4957
產(chǎn)品名稱 ALDH3A2 antibody, 脂肪醛脫氫酶抗體
規(guī) 格 0.2ml
價(jià) 格 1980元
應(yīng) 用 WB,IHC,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細(xì)信息: 說(shuō)明書(shū)下載

Background:  Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Defects in ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS). SLS is an autosomal recessive neurocutaneous disorder characterized by a combination of severe mental retardation, spastic di- or tetraplegia and congenital ichthyosis (increased keratinization). Ichthyosis is usually evident at birth, neurologic symptoms appear in the first or second year of life. Most patients have an IQ of less than 60. Additional clinical features include glistening white spots on the retina, seizures, short stature and speech defects.

Description: Rabbit polyclonal to ALDH3A2

Immunogen: KLH conjugated synthetic peptide derived from ALDH3A2

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 55 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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