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HDJ2 antibody, 熱休克蛋白相關(guān)蛋白4抗體

 
編 號(hào) PR-5471
產(chǎn)品名稱(chēng) HDJ2 antibody, 熱休克蛋白相關(guān)蛋白4抗體
規(guī) 格 0.2ml
價(jià) 格 1980元
應(yīng) 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細(xì)信息: 說(shuō)明書(shū)下載

Background:  DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.

Description: Rabbit polyclonal to HDJ2

Immunogen: KLH conjugated synthetic peptide derived from HDJ2

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 45 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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