會員登陸 / 下載中心
當(dāng)前位置:產(chǎn)品目錄 > 抗體 >> 多克隆抗體
Axin2 antibody, 軸抑制蛋白2抗體

 
編 號 PR-5542
產(chǎn)品名稱 Axin2 antibody, 軸抑制蛋白2抗體
規(guī) 格 0.2ml
價(jià) 格 1980元
應(yīng) 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細(xì)信息: 說明書下載

Background:  β-catenin is a component of both the cadherin cell adhesion system and the Wnt signaling pathway. Wnt signaling increases the amount of β-catenin, by preventing its ubiquitination and degradation, allowing its direct interaction with transcription factors of the lymphoid enhancer factor-T cell factor family and modulation of gene expression. Axin is involved in the degradation of β-catenin by acting as a scaffold to form a complex between β-catenin, adenomatous polyposis coli (APC) and GSK-3β. APC, which is phosphorylated by GSK-3β, induces degradation of β-catenin, thus inhibiting Wnt signal transduction. Conductin is 45% identical to axin and appears to play a similar role to axin in the Wnt signaling pathway.

Description: Rabbit polyclonal to Axin2

Immunogen: KLH conjugated synthetic peptide derived from Axin2

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 94 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

相關(guān)同類產(chǎn)品:

網(wǎng)站首頁 | 公司動態(tài) | 產(chǎn)品中心 | 定制服務(wù) | 代理產(chǎn)品 | 技術(shù)專欄 | 客戶留言 | 聯(lián)系我們

Copyright @ 2011 All Rights Reserved 江蘇鎮(zhèn)江厚普生物科技有限公司 備案/許可證編號為:蘇ICP備11043267號

地址:江蘇省丹陽市呂城工業(yè)園 郵編:212300 電子郵箱:hopebiotech@163.com

訂貨電話:0511-86909515 傳真:0511-86909515 訪問量:20359227