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DR6 antibody, 腫瘤壞死因子受體死亡受體6抗體

 
編 號 PR-1642
產(chǎn)品名稱 DR6 antibody, 腫瘤壞死因子受體死亡受體6抗體
規(guī) 格 0.2ml
價 格 1980元
應 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細信息: 說明書下載

Background:  May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).

Description: Rabbit polyclonal to DR6

Immunogen: KLH conjugated synthetic peptide derived from DR6

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 72 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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