Background:  ACOX1 (acyl-coenzyme A oxidase 1), also known as SCOX or PALMCOX, is a 660 amino acid protein that localizes to the peroxisome and belongs to the acyl-CoA oxidase family. Existing as two alternatively spliced isoforms, ACOX1 uses FAD as a cofactor to catalyze the desaturation of very long chain acyl-CoA proteins to 2-trans-enoyl-CoA proteins, a reaction that utilizes oxygen and produces hydrogen peroxide. Defects in the gene encoding ACOX1 are the cause of pseudoneonatal adrenoleukodystrophy (pseudo-NALD), which is a single-enzyme disorder that is characterized by seizures, mental retardation, leukodystrophy, mild hepatomegaly and hearing deficits.

Description: Rabbit polyclonal to ACOX1

Immunogen: KLH conjugated synthetic peptide derived from ACOX1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 74 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.